CBD Oil in Parkinson’s Disease
- CBD and Parkinson’s disease
- Parkinson’s Disease
- Treatment options
- Side effects
- CBD Products in Parkinson’s Disease
- Most frequent questions about CBD
It is a neurological disease in which nerve cells gradually decrease in the brain. This leads to serious problems with, for example, movement control and other accompanying symptoms. Unfortunately, the treatment of Parkinson’s disease is in the dark. Patients are currently receiving uncomfortable information about their average life expectancy from 6 to 9 years. However, they can still be helped to survive this period with the least possible health problems. And that’s what CBD is for at Parkinson’s disease.
How does CBD help with Parkinson’s
Experience with CBD oil in Parkinson’s disease has shown that this substance can positively affect several symptoms of the disease. These include:
- improvement of appetite,
- elimination of insomnia,
- depression or anxiety,
- anti-inflammatory effect,
- pain relief or reduction of cramps.
On the Internet you will also find a number of forums on the topic of CBD and Parkinson’s disease to help answer all questions. Cannabis products in Parkinson’s disease are currently extremely effective and popular. Medical cannabis in Parkinson can be a great way to prevent side effects of other drugs and allow you to spend treatment in a much better physical or mental condition.
Parkinson’s disease is a progressive, degenerative disease of the peripheral (PNS) and central (CNS) nervous systems. It most often occurs around the age of 60. However, in early onset Parkinson’s disease, it manifests itself in approximately 10% of cases before reaching the age of 40 years. A unique phenomenon is Juvenile Parkinsonism, which occurs even before the 20th year. In this case, it is probably a congenital form of disease associated with specific gene mutations.
In Europe alone, around 1.2 million people are diagnosed with PD. This ranks it second in the list of neurodegenerative diseases.
Primary symptoms of Parkinson’s include:
- muscle stiffness,
- shuffling instead of walking, slowing of movement, and imbalance.
Atypical symptoms of Parkinson’s include:
- anxiety and depression.
When we mention the risk factors for Parkinson’s disease, we cannot forget about age. But scientists also include toxic substances or infections in triggers. Life expectancy in Parkinson’s disease depends on its course and species.
Lewy Bodies Dementia
In Dementia with Lewy Bodies (DLB) and Parkinson’s disease with dementia, the average survival time is about 7 years.
In multisystemic atrophy (sporadic progressive neurodegenerative disease with a combination of parkinsonism, autonomic dysfunction and cerebellar manifestations), the median survival is 6-9 years. However, death in Parkinson’s disease may occur earlier, for example due to accidents.
A positive family history in Parkinson’s disease is found in about 10 to 15% of patients. Congitive disorders, especially dementia syndrome, are a major inconvenience. It is characterized as a deficit in at least two areas:
- visionary social orientation,
- verbal ability,
- executive functions,
These deficits consequently lead to an overall reduction in intellectual abilities and negatively affect standard daily activities. This is accompanied by psychotic symptoms or personality changes in Parkinson’s disease.
Patients have the possibility to apply for the issuance of a card of a natural person with severe disabilities. In order for the document control in Parkinson’s disease to be smooth, the insured person must have a proven long-term unfavorable health condition, which has caused his/her decrease in the ability to perform a gainful activity to be determined by an medical appraiser. The issuance of a card shall promote the social integration of a natural person with severe disabilities into society and the maintenance of his or her human dignity.
Treatment of Parkinson’s Disease, Medicines and Cures
At present, every more advanced country already has all possible conventional therapeutic options for treating Parkinson’s disease. However, it cannot be cured completely. In the early stages, the principle of treatment is mainly considered to be the replacement of absent dopamine with specific transdermal patches or medications. However, other symptoms such as cognitive impairment, sexual activity, depression or anxiety should also be considered during treatment.
Pumping systems and deep brain stimulation are used for advanced stages of the disease. It’s built to introduce electrodes into the deeper structures of the brain. These are then stimulated by a neurostimulator. Stimulation is a way to reduce the dose of medicines, thereby preventing unpleasant side effects. Pumping systems continuously deliver medication through a pump to the small intestine or subcutaneously. Their advantage is the elimination of motor fluctuations that occur during advanced stages of the disease.
No matter what form of treatment it is, special rehabilitation is always necessary. There can be no lack of psychological support for patients or dietary adjustment. Again, it is important that the patient accepts the existence of the disease and the entire course of treatment as necessary.
Parkinson’s disease drugs
The most commonly used medicines in the treatment of Parkinson’s disease include:
Levodopa is considered the most effective active substance in most cases. It is an amino acid similar to the basic building blocks of proteins. At the first moment, it is absorbed into the bloodstream and then the interface between blood and brain tissue passes. It turns chemically into dopamine in the brain. Changes in the symptoms of Parkinson’s disease were achieved by adjusting the amount of dopamine to almost normal values. Levodopa is suitable for most patients and almost all symptoms.
The combination of Levodopa with Carbidopa will eliminate the side effects of the active substance. In some cases, nausea occurs, which is caused by the substance dopamine, but which arises outside the brain, where it does not even have therapeutic effects. Carbidopa blocks the conversion of levodopa to dopamine. Anticholinergics inhibit the action of the neurotransmitter acetylchiline. Amantadine is a chemical that has multiple effects in the brain, increases dopamine release and has antichilnergic effects. Selegiline prolongs the effects of dopamine and can intensify them.
Most frequent questions about CBD
CBD Products in Parkinson’s Disease
Many studies have shown that cannabis plants also have a number of health benefits for the human body. CBD, which is also suitable for the treatment of Parkinson’s disease, is particularly effective. It can treat its specific symptoms, such as impaired movement, sleep disorders or psychosis. This is due to a system of specific receptor triggers. Important active substances can also be introduced into the patient’s body by CBD products, for example. Most endocannabinoids are formed in the brain, nervous system or spinal cord, precisely these organs are attacked by Parkinson’s disease. It is therefore advisable to deliver these substances to the body by external means, for example, through CBD cannabidiol drops.
Effects of CBD
We will find several versions on the market today. CBD capsules, drops or CBD oil are suitable. There are five basic effects on the symptoms of the disease:
- Reduction of spasms in the smooth muscles of the abdominal cavity (elimination of constipation), limbs, back muscles or relaxation of stiffness and spasms of the tongue and mimic muscles. Thus, the patient has improved speech, chewing skills and is able to change facial expressions (it often happens that during treatment they have a face almost completely devoid of expression).
- Pain relief due to activation of CB1 receptors in the back, neck or head areas.
- Anti-inflammatory effects by activation of CB2 receptors (reduction of dopamine production occurs in inflammation of the brain)
- Insomnia, which occurs in behavioral disorders in REM sleep phases. These arise from the inability to achieve physical tranquility during sleep. CDB products also help with anxiety or depression
- Improvement of appetite, thanks to which there is no drastic loss of fat and muscle mass or weight loss, thus the patient has more physical strength and activity.
Side effects of CBD
Due to the lack of completed clinical trials of CBD, it is impossible to claim that CBD has no serious side effects.
Some of the minor side effects that can occur while taking CBD products are:
- dry mouth
- low blood pressure
- light headedness